Viral etiology and risk factors for severe community-acquired pneumonia in children / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 449-453, 2012.
Article
Dans Chinois
| WPRIM
| ID: wpr-320623
ABSTRACT
<p><b>OBJECTIVE</b>To study the virus spectrum of severe community-acquired pneumonia (CAP) and risk factors for the disease in children.</p><p><b>METHODS</b>Respiratory secretion specimens were collected from 1096 children hospitalized with CAP from June 2007 to November 2008, including 100 cases of severe CAP. Respiratory viruses were detected by PCR, nest-PCR or RT-PCR. Clinical data on the children were analyzed by univariate and multivariate logistic regression analysis for examining risk factors for severe CAP.</p><p><b>RESULTS</b>Viral pathogens were isolated from 82 (82%) of the 100 cases with severe CAP. RSV was the most common (37%), followed by HBoV (25%) and HRV (18%). Mixed infection was noted in 32 cases (32%). The presence of underlying diseases (OR=6.623, P<0.01) and RSV infection (OR=1.672, P<0.05) were risk factors for severe CAP in children, while age was a protective factor (OR=0.475, P<0.01).</p><p><b>CONCLUSIONS</b>RSV is the most frequent viral pathogen in children with severe CAP. The presence of underlying diseases and RSV infection may be risk factors for severe CAP, while age is a protective factor.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pneumopathie virale
/
Virus respiratoires syncytiaux
/
Virologie
/
Modèles logistiques
/
Facteurs de risque
/
Infections communautaires
/
Bocavirus humain
Type d'étude:
Etude d'étiologie
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Enfant d'âge préscolaire
/
Femelle
/
Humains
/
Bébé
/
Mâle
/
Nouveau-né
langue:
Chinois
Texte intégral:
Chinese Journal of Contemporary Pediatrics
Année:
2012
Type:
Article
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