Association between different types of obesity and cardiovascular risk factors in school-aged children / 中华流行病学杂志

ABSTRACT

Objective The aim of this paper was to analyze the association between different types of obesity and cardiovascular risk factors (CRFs) in school-aged children.Methods 3508children aged 6-18 years old including 2 054 non-obese and 1 454 obese children were chosen as the population under study,from Beijing Children and Adolescents Metabolic Syndrome Study.Demographic data was collected through questionnaires while height,weight,waist circumference,and blood pressure were measured through physical check-up.Fasting blood glucose and blood lipids were also tested.Children were divided into four groupswithout obesity,with general obesity,with abdominal obesity and with combined obesity.CRFs including dyslipidemia,impaired fasting glucose (IFG),and hypertension were scored.Multiple linear regression and logistic regression analyses were performed to assess the association between different types of obesity and CRFs.Results From non-obese children,children under general-obesity,abdominal obesity and those with combined types of obesity,there appeared an increasing trend in the levels of blood pressure,blood glucose,and blood lipids,the prevalence dyslipidemia and hypertension (P＜0.001).There were no significant differences in the risks of IFG among four types of obesity.After controlling for age,sex,and puberty stage,when compared with non-obese children,those children with abdominal obesity or combined types of obesity had 1.54 and 2.51 times of risks to only one CRF,while generally obese children had similar risk of dyslipidemia.When compared to the non-obese ones,children with general obesity,abdominal obesity,or combined types of obesity showed 3.32,2.21 and 7.42 times of risks to ≥2CRFs and 3.10,3.67 and 10.75 times of risks to ≥3 CRFs.The cluster of CRFs increased with the levels of obesity (P＜0.001).Conclusion Levels and cluster of CRFs were increasing along with the levels of obesity in school-aged children in Beijing.Children with combined types of obesity had the highest risk of clustering CRFs,followed by those with abdominal obesity and general obesity.