Effect of micronutrients on the immune status of human immunodeficiency virus-positive individuals / 中国医学科学院学报

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the effect of micronutrients on the immune status of human immunodeficiency virus (HIV)-positive individuals.</p><p><b>METHODS</b>Totally 102 HIV-positive individuals were randomly divided into supplementation group (received micronutrients supplement) and control group (received placebo). Physical examinations were performed at baseline and at the end of the trial. Immune status were determined in both two groups.</p><p><b>RESULTS</b>Age, height, weight, and sex ratio were not significantly different between two groups (all P>0.05). Baseline CD3+, CD4+, and CD8+ T lymphocytes and IgA, IgG, IgM, C3 levels were not significantly different between two groups (all P>0.05), while the levels of CD3+, CD4+, and CD8+ T lymphocytes and IgA, IgG, IgM, C3 were significantly higher in supplementation group than in control group(all P0.05).</p><p><b>CONCLUSION</b>Supplementation of micronutrients can improve the immune status of HIV-positives individuals.</p>