Correlation of age and sex hormones to the transition zone volume of the prostate / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the correlation of age and sex hormones to the total volume (TV) and transition zone volume</p><p><b>METHODS</b>Eighty-two men were divided into two groups with the age of 60 as the dividing line. Prostatic TV (TZV and TZV were measured with transrectal ultrasound (TRUS) and the concentrations of total testosterone (T), free testosterone (fT) and estradiol (E2) were measured with radioimmunoassay. Exponential curve regression and one-factor analysis of variance (ANOVA) were used for statistical analysis.</p><p><b>RESULTS</b>Age was significantly correlated with TV, TZV and the TZV/TV ratio, P < 0.01. There was a significant positive correlation between the concentrations of fT and TZV, a negative correlation between those of E2 and TZV (P < 0.01), but no correlation between those of T and TZV (P > 0.05).</p><p><b>CONCLUSION</b>The significant acceleration of the TZV of the prostate after the age of 60 is related to sex hormones.</p>