Analysis of the factors related to glomerular filtration rate in type 2 diabetes without albuminuria / 南方医科大学学报
Journal of Southern Medical University
;
(12): 2502-2504, 2010.
Article
Dans Chinois
| WPRIM
| ID: wpr-323623
ABSTRACT
<p><b>OBJECTIVE</b>To analyze the risk factors affecting the glomerular filtration rate (GFR) in type 2 diabetic patients without albuminuria.</p><p><b>METHODS</b>A total of 131 type 2 diabetic patients with normal urinary albumin excretion rate (UAER) were divided into normal GFR group and decreased GFR group. The factors relevant to GFR were analyzed by multiple factors regression.</p><p><b>RESULTS</b>Age, course of diabetes, systolic blood pressure, prevalence of hypertension, the level of serum creatinine (SCr), blood urea nitrogen (BUN) and uric acid (UA) were significantly higher in decreased GFR group than in normal GFR group. Multivariate regression showed that SCr, age, systolic blood pressure, and UA were negatively correlated to GFR.</p><p><b>CONCLUSION</b>Reduced GFR occurs in some type 2 diabetic patients without albuminuria. SCr, age, systolic blood pressure and UA are the major factors related to decreased GFR. The degree of early renal damage in diabetic patients can be better evaluated by combining GFR and UAER.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Épidémiologie
/
Prévalence
/
Facteurs de risque
/
Diabète de type 2
/
Néphropathies diabétiques
/
Albuminurie
/
Débit de filtration glomérulaire
/
Rein
Type d'étude:
Etude d'étiologie
/
Étude de prévalence
/
Facteurs de risque
Limites du sujet:
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Journal of Southern Medical University
Année:
2010
Type:
Article
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