Determination of HPLC fingerprint of Qingfengtong capsule / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 2492-2493, 2007.
Article
Dans Chinois
| WPRIM
| ID: wpr-324344
ABSTRACT
<p><b>OBJECTIVE</b>To establish a fingerprint analysis method of Qingfengtong capsule by HPLC.</p><p><b>METHOD</b>The samples were extracted with 70% ethanol in an ultrasonic bath. The extracts were analyzed at 35 degrees C on a Diamonsil C18 column (4.6 mm x 250 mm, 5 microm) with 0.1 mol x L(-1) potassium dihydrogen phosphate water-solution as mobile phase A, and methanol as mobile phase B. The analysis followed a linear gradient elution program. Initial condition of the mobile phase was 10% B for 2 minutes; then changed to 90% B in 40 minutes. The flow rate was kept at 1.0 ml x min(-1) and the detector wavelength was 262 nm.</p><p><b>RESULT</b>The main peaks in fingerprint chromatogram of Qingfengtong capsules were separated fairly well. The results of method validation meet the requirements for the fingerprints.</p><p><b>CONCLUSION</b>The established method can be used for the quality control of Qingfengtong capsules.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Plantes médicinales
/
Contrôle de qualité
/
Normes de référence
/
Capsules
/
Médicaments issus de plantes chinoises
/
Chimie
/
Reproductibilité des résultats
/
Chromatographie en phase liquide à haute performance
/
Salvia miltiorrhiza
/
Epimedium
langue:
Chinois
Texte intégral:
China Journal of Chinese Materia Medica
Année:
2007
Type:
Article
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