Mechanism of intravenous immunoglobulin therapy for severe hand-foot-mouth disease: a review / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 712-716, 2011.
Article
Dans Chinois
| WPRIM
| ID: wpr-324546
ABSTRACT
Hand-foot-mouth disease (HFMD) is an acute infectious disease caused by various enteroviruses. Recently, large HFMD outbreaks caused by enterovirus type 71 (EV71) have been frequently reported in China, posing great threats on children's health. There is no specific antiviral therapy for severe HFMD, and patient management mainly depends on supportive and symptomatic treatment. Intravenous immunoglobulin (IVIG) is a pharmaceutical preparation of human IgG that is pooled from thousands of healthy blood donors, and contained neutralization antibodies against various enteroviruses, including EV71. IVIG therapy should be carefully administrated for severe HFMD considering its role on passive immunization against EV71 and immune regulation.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Thérapeutique
/
Virologie
/
Immunisation passive
/
Immunoglobulines par voie veineuse
/
Entérovirus humain A
/
Utilisations thérapeutiques
/
Allergie et immunologie
/
Anticorps neutralisants
/
Syndrome mains-pieds-bouche
/
Anticorps antiviraux
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Chinese Journal of Biotechnology
Année:
2011
Type:
Article
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