Analysis on therapeutic effect of Western and Chinese drug in treating intrahepatic cholestasis pregnancy / 中国中西医结合杂志

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the therapeutic effect of Yinchenghao decoction (YCHD) and S-adenosy-L-methionine (SAM) in treating intrahepatic cholestasis of pregnancy (ICP) and improving prognosis of perinatal newborn babies.</p><p><b>METHODS</b>Sixty in-patients of ICP were randomly divided into two groups, the group A treated with YCHD and the group B treated with SAM. The symptom of itching and serum biochemical indexes, including glycocholic acid, bilirubin and transaminase, were observed after 3 weeks treatment, and the prognosis of perinatal newborn babies between the two groups was compared after delivery.</p><p><b>RESULTS</b>After treatment, the symptom of itching, serum levels of glycocholic acid, bilirubin and transaminase improved significantly (P < 0.05) in both groups, and the prognosis of newborn in the two groups was similar (P > 0.05).</p><p><b>CONCLUSION</b>Both YCHD and SAM could effectively treat ICP. The former is rather cheaper, so it is more feasible for spreading.</p>