Effect of nitric oxide in vestibular compensation / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 612-614, 2003.
Article
Dans Chinois
| WPRIM
| ID: wpr-327025
ABSTRACT
<p><b>OBJECTIVE</b>To study the effect of nitric oxide (NO) in vestibular compensation after unilateral vestibular deafferentation.</p><p><b>METHODS</b>Eighteen animals were divided into two groups, 6 of group a as control, 12 of group b received gentamicin intratympanic injection in the left ear. Half of the animals were killed respectively after 5 days and 10 days. Vestibular endorgan and brainstem tissue sections were subjected to NADPH-d reactive test of NOS for histochemical examination.</p><p><b>RESULTS</b>In group a, NOS-like reactivity in both sides of vestibular endorgan and nucli. In group b during 5 days, NOS-like reactivity in right side of vestibular endorgan and nucli, those of the left side were negative. During 10 days, NOS-like reactivity only in the right side of vestibular endorgan.</p><p><b>CONCLUSIONS</b>Changes of NOS expression in the contralateral vestibular nucli might have played a role in vestibular compensation.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Nerf vestibulaire
/
Plaies et blessures
/
Tronc cérébral
/
Noyaux vestibulaires
/
Adaptation physiologique
/
Gentamicine
/
Labyrinthe vestibulaire
/
Potentiels évoqués auditifs du tronc cérébral
/
Nitric oxide synthase
/
Cochons d'Inde
Limites du sujet:
Animaux
langue:
Chinois
Texte intégral:
Acta Academiae Medicinae Sinicae
Année:
2003
Type:
Article
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