Difference of dilation resistance to coronary stenting between fibrous plaques and lipid-rich plaques / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 4149-4153, 2013.
Article
Dans Anglais
| WPRIM
| ID: wpr-327616
ABSTRACT
<p><b>BACKGROUND</b>Dilation resistance to stenting in non-calcified coronary plaques was compared in patients with percutaneous coronary intervention (PCI) in order to confirm the clinical usefulness of multislice computed tomography in examining coronary plaque type and to provide information pertaining to the effects of plaque type on dilatation resistance.</p><p><b>METHODS</b>A retrospective analysis of 64-slice computed tomography coronary imaging data collected in the month prior to coronary stenting in 93 patients (65 male and 28 female, mean age of (57.22±7.22) years) was conducted. Non-calcified coronary plaques were divided into lipid-rich (lipid content >25% of plaque volume) and fibrous plaques according to the Hammer-Hansen S method:
where lipids, fiber, and intraluminal components were indicated by contrast using Hu values of -100-49, 50-129, and >130, respectively. Clinical features, pre-dilatation balloon specifications and filling pressure, and stent size and release pressure were compared.</p><p><b>RESULTS</b>High-sensitivity C-reactive protein levels were higher in the lipid-rich plaque group. In patients with typical symptoms, unstable angina was more commonly observed in the lipid-rich plaque group. No significant differences in low density lipoprotein, pre-dilatation balloon specifications, pre-dilatation pressure, or stent specifications were observed. Stent release pressure in the lipid-rich plaque group ((1130.16±202.04) kPa), was significantly lower than that observed in the fibrous plaque group ((1240.61±193.29) kPa, P = 0.009).</p><p><b>CONCLUSION</b>Softer, lipid-rich plaques exhibit lower dilation resistance during stenting in PCI patients.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Physiologie
/
Chirurgie générale
/
Maladie des artères coronaires
/
Protéine C-réactive
/
Études rétrospectives
/
Coronarographie
/
Plaque d'athérosclérose
/
Tomodensitométrie multidétecteurs
/
Intervention coronarienne percutanée
Type d'étude:
Étude observationnelle
Limites du sujet:
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Chinese Medical Journal
Année:
2013
Type:
Article
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