Simultaneous determination of chlorogenic acid, cryptochlorogenic acid, caffeic acid, naringin, hesperidin and linarin in xiao'erjinning oral liquid by an HPLC method / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1702-1705, 2010.
Article
Dans Chinois
| WPRIM
| ID: wpr-328077
ABSTRACT
<p><b>OBJECTIVE</b>To develop a HPLC method for the simultaneous determination of chlorogenic acid, cryptochlorogenic acid, caffeic acid, naringin, hesperidin and linarin in xiao' erjinning oral liquid.</p><p><b>METHOD</b>The chromatographic separation was achieved on a Lichrospher C18 (4.6 mm x 250 mm, 5 microm) column with a mobile phase which was composed of acetonitrile(A) and 0.4% phosphoric acid(B) for gradient elution (1090-1882-2773). The flow rate was (0.8-1.1-0.8) mL x min(-1), the column temperature was 30 degrees C and the detection wavelength was set at 300 nm.</p><p><b>RESULT</b>The results showed that 6 effective components were separated well and showed good linearity. The average recoveries were between 95%-105%.</p><p><b>CONCLUSION</b>The method is proved to be rapid, accurate, credible and repeatable. It can be used for the quality control of Xiao'erjinning oral liquid.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Acides caféiques
/
Médicaments issus de plantes chinoises
/
Acide chlorogénique
/
Chromatographie en phase liquide à haute performance
/
Flavanones
/
Formes posologiques
/
Hétérosides
/
Hespéridine
/
Méthodes
langue:
Chinois
Texte intégral:
China Journal of Chinese Materia Medica
Année:
2010
Type:
Article
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