Cytocompatibility of nanophase hydroxyapatite ceramics / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 456-459, 2004.
Article
Dans Chinois
| WPRIM
| ID: wpr-330022
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the cytocompatibility of nanophase hydroxyapatite ceramics in vitro.</p><p><b>METHODS</b>Hydroxyapatite (HA) was prepared via wet method. The grain size of the hydroxyapatite in the study was determined by scanning electron microscope and atomic force microscope with image analysis software. Primary osteoblast culture was established from rat calvaria. Cell adherence and proliferation on nanophase hydroxyapatite ceramics and conventional hydroxyapatite ceramics were examined at 1, 3, 5, 7 days. Morphology of the cells was observed by microscope.</p><p><b>RESULTS</b>The average grain size of the nanophase and conventional HA was 55 nm and 780 nm, respectively. Throughout 7 days period, osteoblast proliferation on the HA was similar to that on tissue culture borosilicate glass controls, osteoblasts could attach, spread and proliferate on HA. However, compared to conventional ceramics, osteoblast proliferation on nanophase HA was significantly better after 1, 3, 5 and 7 days.</p><p><b>CONCLUSION</b>Cytocompatibility of nanophase HA was significantly better than conventional ceramics.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Ostéoblastes
/
Matériaux biocompatibles
/
Adhérence cellulaire
/
Cellules cultivées
/
Céramiques
/
Durapatite
/
Biologie cellulaire
/
Prolifération cellulaire
/
Nanostructures
Limites du sujet:
Animaux
langue:
Chinois
Texte intégral:
West China Journal of Stomatology
Année:
2004
Type:
Article
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