Correlation of serum cystatin C with blood pressure: a cross-sectional study of 912 subjects / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1055-1058, 2015.
Article
Dans Chinois
| WPRIM
| ID: wpr-333684
ABSTRACT
<p><b>OBJECTIVE</b>To study the association between serum cystatin C level and blood pressure.</p><p><b>METHODS</b>We conducted a cross-sectional study of 912 subjects randomly sampled from a cohort visiting for routine physical examinations. The epidemiological data were obtained using questionnaires and from the database of physical examination results. Pearson analysis and multiple stepwise regression analysis were used to analyze the relationship between blood pressure and cystatin C.</p><p><b>RESULTS</b>The levels of serum cystatin C differed significantly among the normotensive, prehypertensive, and hypertensive subjects (P<0.05). Pearson analysis revealed that regardless of gender, serum cystatin C was positively correlated with SBP, DBP, MAP, BMI, TC, TG, LDL-C, UA and BUN (P<0.05). With MAP, SBP and DBP as dependent variables, multiple stepwise regression analysis of the factors affecting blood pressure indicated that cystatin C had the strongest effect on SBP and MAP (P<0.05) but did not significantly affect DBP (P>0.05).</p><p><b>CONCLUSION</b>Serum cystatin C level is significantly correlated with SBP and MAP and can be used as a biomarker for alert of hypertension.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Sang
/
Pression sanguine
/
Marqueurs biologiques
/
Études transversales
/
Cystatine C
/
Hypertension artérielle
Type d'étude:
Étude observationnelle
/
Étude de prévalence
/
Facteurs de risque
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Southern Medical University
Année:
2015
Type:
Article
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