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Effects of delayed opening of infarct-related artery on late left ventricular remodeling in patients with acute anterior myocardial infarction / 中华心血管病杂志
Chinese Journal of Cardiology ; (12): 328-331, 2005.
Article Dans Chinois | WPRIM | ID: wpr-334708
ABSTRACT
<p><b>OBJECTIVE</b>To assess the effect of delayed opening of the infarct-related artery (IRA) by percutaneous coronary intervention (PCI) on the late left ventricular remodeling after acute anterior myocardial infarction (AAMI).</p><p><b>METHODS</b>Sixty four patients with initial Q-wave AAMI and with the total occluded IRA conformed by angiogram at 9.1 +/- 2.3 (2 - 14) days after the onset were divided into successful PCI group and control group (not receiving PCI or the IRA not re-opened). Two-D echocardiogram was performed at acute phase (about 3 weeks), 2 and 6 months after onset of AAMI respectively to detect the left ventricular function and left ventricular wall motion abnormality (VWMA). The total congestive heart failure events were recorded during 6 months follow-up.</p><p><b>RESULTS</b>VWMA scores, left ventricular ejection fraction (LVEF), left ventricular end-diastolic and end-systolic volume indexes (LVEDVI and LVESVI) were similar in 2 groups at acute phase and 2 months after the onset of AAMI. There were no differences between the parameters above at acute phase and 2 months in each group too. VWMA scores and LVEF did not changed significantly at 6 months in each group compared with those at acute phase and 2 months (P > 0.05). But LVEDVI and LVESVI were significantly smaller in the successful PCI group than those in the control group (P < 0.01, P < 0.05). The rate of congestive heart failure events was 19% in control group and 2.0% in successful PCI group (P > 0.05) respectively.</p><p><b>CONCLUSIONS</b>Delayed opening of IRA in AAMI could prevent the late phase but not the early phase of left ventricular remodeling after AMI.</p>
Sujets)
Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Anatomopathologie / Thérapeutique / Reperfusion myocardique / Angioplastie coronaire par ballonnet / Remodelage ventriculaire / Infarctus du myocarde Limites du sujet: Adulte très âgé / Aged80 / Femelle / Humains / Mâle langue: Chinois Texte intégral: Chinese Journal of Cardiology Année: 2005 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Anatomopathologie / Thérapeutique / Reperfusion myocardique / Angioplastie coronaire par ballonnet / Remodelage ventriculaire / Infarctus du myocarde Limites du sujet: Adulte très âgé / Aged80 / Femelle / Humains / Mâle langue: Chinois Texte intégral: Chinese Journal of Cardiology Année: 2005 Type: Article