A case of Gitelman syndrome with severe hyponatraemia and hypophosphataemia
Singapore medical journal
;
: e18-20, 2013.
Article
Dans Anglais
| WPRIM
| ID: wpr-335456
ABSTRACT
Gitelman syndrome (GS) is a renal tubular disorder of the thiazide-sensitive sodium chloride cotransporter, which is located in the distal tubule of the loop of Henle. We present a rare case of GS complicated by severe hyponatraemia and hypophosphataemia. A 17-year-old boy was admitted to our institution with fever and lethargy. The workup revealed typical features of GS, i.e. hypokalaemia, hypomagnesaemia and metabolic alkalosis. In this report, we discuss the differential diagnoses and rationale for accepting GS as the most likely diagnosis. This case was complicated by severe hyponatraemia (115 mmol/L) and hypophosphataemia (0.32 mmol/L). We concluded that the syndrome of inappropriate secretion of antidiuretic hormones could not be ruled out and that respiratory alkalosis was the most likely aetiology of hypophosphataemia. This case report also generates an interesting discussion on water and electrolyte metabolism.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Vasopressines
/
Hypophosphatémie
/
Sécrétions corporelles
/
Diagnostic
/
Électrolytes
/
Alcalose respiratoire
/
Léthargie
/
Syndrome de Gitelman
/
Fièvre
/
Hyponatrémie
Type d'étude:
Etude diagnostique
Limites du sujet:
Adolescent
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Singapore medical journal
Année:
2013
Type:
Article
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