Immunophenotypic characteristics of multiple myeloma cells / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 226-228, 2002.
Article
Dans Chinois
| WPRIM
| ID: wpr-337604
ABSTRACT
To investigate the immunophenotypic characteristics of multiple myeloma (MM) cells, 20 bone marrow samples from patients with multiple myeloma were analyzed by flow cytometry with three-color direct immunofluorescence staining. Results showed that all of myeloma cells expressed bright CD38, dim or negative CD45 and negative CD19. Most of the cells were CD56(+) and a small portions were ckappa(+) or clambda(+), or CD20(+). The phenotypes of normal plasmocyte, CD19(+) and CD56(-), except CD56(-) in one-third samples, were not appeared in all detected samples. It was concluded that the surface marker analysis of myeloma cells is a useful tool for diagnosis and further evaluating prognosis of multiple myeloma.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Cellules de la moelle osseuse
/
Glycoprotéines membranaires
/
Antigènes CD
/
Immunophénotypage
/
Antigènes CD45
/
Antigènes CD56
/
Antigènes CD20
/
Antigènes CD19
/
ADP-ribosyl cyclase
/
Allergie et immunologie
Type d'étude:
Étude pronostique
Limites du sujet:
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Journal of Experimental Hematology
Année:
2002
Type:
Article
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