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Activation of random-donor platelet concentrates and platelet prepared from random-donor apheresis collections during storage / 中国实验血液学杂志
Journal of Experimental Hematology ; (6): 458-461, 2002.
Article Dans Chinois | WPRIM | ID: wpr-337646
ABSTRACT
The activation of random-donor platelet concentrates and platelets prepared from random-donor apheresis collections (plateletpheresis) during storage were studied. Percentage of CD62p staining and mean channel fluorescence (MCF) of CD41 of two kinds of platelets during storage on day 0, day 1, day 3 and day 5 were determined by flow cytometry. The results showed that percentages of CD62p staining and MCF of CD41 in plateletpheresis were (18.91 +/- 6.25)%, (19.48 +/- 8.27)%, (22.82 +/- 6.06)%, (56.71 +/- 11.79)% and (8.09 +/- 2.38)%, (8.13 +/- 2.45)%, (8.44 +/- 2.51)%, (19.87 +/- 6.13)%, while the results of platelet concentrates were (30.65 +/- 12.33)%, (31.46 +/- 11.86)%, (32.51 +/- 13.05)%, (63.55 +/- 13.27)% and (10.33 +/- 4.37)%, (11.09 +/- 6.61)%, (13.46 +/- 9.69)%, (24.41 +/- 10.15)%, respectively. The platelet count and pH value were also determined. The platelet number, pH value, percentage of CD62p staining and MCF of CD41 had no significant difference within 3 days of platelet storage. The platelet number and pH value decreased significantly (P < 0.001), while percentages of CD62p staining and MCF of CD41 increased significantly (P < 0.001) on day 5 of storage. It is concluded that the quality of plateletpheresis is better than platelet concentrate.
Sujets)
Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Sang / Donneurs de sang / Conservation de sang / Activation plaquettaire / Thrombocytaphérèse / Sélectine P / Glycoprotéine-IIb de membrane plaquettaire Type d'étude: Essai clinique contrôlé Limites du sujet: Humains langue: Chinois Texte intégral: Journal of Experimental Hematology Année: 2002 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Sang / Donneurs de sang / Conservation de sang / Activation plaquettaire / Thrombocytaphérèse / Sélectine P / Glycoprotéine-IIb de membrane plaquettaire Type d'étude: Essai clinique contrôlé Limites du sujet: Humains langue: Chinois Texte intégral: Journal of Experimental Hematology Année: 2002 Type: Article