Plasma endothelin-1 in patients with prostate cancer and its clinical significance / 中华男科学杂志
National Journal of Andrology
;
(12): 315-322, 2006.
Article
Dans Chinois
| WPRIM
| ID: wpr-338304
ABSTRACT
<p><b>OBJECTIVE</b>To investigate plasma endothelin-1 (ET-1) level in patients with prostate cancers and its clinical significance.</p><p><b>METHODS</b>Plasma ET-1 level was measured by radioimmunoassay in 31 patients of prostate cancer (23 with non-HRPC, 8 with HRPC) and 26 patients of BPH.</p><p><b>RESULTS</b>Compared with each other of the ET-1 level, there were no significant difference among the BPH group,non-HRPC group and HRPC group. No significant difference was found either between bone metastasis (BM) and non- BM, between high and middling differentiation prostate cancer group, as well as in different PSA level groups (P >0.05). But the ET-1 level in low differentiation prostate cancer was notably lower than those of the high and middle respectively (P < 0.05).</p><p><b>CONCLUSION</b>To detect plasma endothelin-1 (ET-1) level is not a useful method to evaluate the development and the prognosis of prostate cancer.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pronostic
/
Hyperplasie de la prostate
/
Tumeurs de la prostate
/
Sang
/
Dosage radioimmunologique
/
Endothéline-1
Type d'étude:
Étude pronostique
Limites du sujet:
Adulte très âgé
/
Aged80
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
National Journal of Andrology
Année:
2006
Type:
Article
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