Study on HPLC characteristic fingerprint of active components of dachuanxiong fang in plasma and cerebrospinal fluid / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 2017-2021, 2012.
Article
Dans Chinois
| WPRIM
| ID: wpr-338713
ABSTRACT
<p><b>OBJECTIVE</b>To establish an accurate and simple qualitative analytical method in vivo in the study on HPLC characteristic fingerprint of active components of dachuanxiong fang in plasma and cerebrospinal fluid, in order to lay a foundation for studies on components found in plasma and cerebrospinal fluid and provide basis for compatible regularity of initiators.</p><p><b>METHOD</b>HPLC characteristic fingerprint of active components of dachuanxiong fang in plasma and cerebrospinal fluid was established.</p><p><b>RESULT</b>The similarity of fingerprints of all of six batches of samples was above 0.85, RSD of their relative retention times in common peaks was less than 2. 0%.</p><p><b>CONCLUSION</b>The fingerprints of active components of dachuanxiong fang in plasma and cerebrospinal fluid were stable and accurate that they can be used in qualitative analysis on in vivo components.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Contrôle de qualité
/
Sang
/
Médicaments issus de plantes chinoises
/
Extraits de plantes
/
Liquide cérébrospinal
/
Chromatographie en phase liquide à haute performance
/
Rat Sprague-Dawley
/
Médecine traditionnelle chinoise
/
Métabolisme
/
Méthodes
Type d'étude:
Etude diagnostique
/
Recherche qualitative
Limites du sujet:
Animaux
langue:
Chinois
Texte intégral:
China Journal of Chinese Materia Medica
Année:
2012
Type:
Article
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