Mortality Predictors in Patients Treated with Continuous Renal Replacement / 대한신장학회지
Korean Journal of Nephrology
;
: 73-79, 2011.
Article
Dans Coréen
| WPRIM
| ID: wpr-34000
ABSTRACT
PURPOSE:
Acute kidney injury (AKI) is a frequent condition with a high mortality rate that requires continuous renal replacement therapy (CRRT). We evaluated the Simplified Acute Physiology Score 3 (SAPS 3) and Acute Physiology and Chronic Health Evaluation II (APACHE II) score, determined at the start of CRRT, for predicting mortality in AKI.METHODS:
We retrospectively analyzed the demographic, clinical, and laboratory data of 89 patients with AKI or acute-on-chronic kidney disease who received CRRT between September 2006 and September 2009. We calculated the SAPS 3 and APACHE II score at the start of CRRT.RESULTS:
The average age of the 89 patients was 64.4+/-13.9 (17-92) years. Fifty-nine (66.3%) were male. Eighteen (20.2%) patients had chronic kidney disease and 30 (33.7%) had diabetes. The overall mortality was 75.3%. The average SAPS 3 was 89.4+/-14.9 and the average APACHE II score was 28.4+/-5.2. The SAPS 3 was higher in non-survivors than survivors (p=0.038). Infection was more common in non-survivors (p=0.036). There were no significant differences between the two groups for other conditions. The variables influencing mortality on univariate analysis were SAPS 3 and presence of infection. The area under the receiver-operating characteristic curve for SAPS 3 was 0.69 (95% CI. 0.54-0.83). At a SAPS 3 of 84, the sensitivity for predicting mortality was 71.6% and the specificity was 69.2%.CONCLUSION:
The SAPS 3 determined before starting CRRT could be a predictor of hospital mortality in patients with AKI.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Études rétrospectives
/
Sensibilité et spécificité
/
Mortalité hospitalière
/
Survivants
/
Traitement substitutif de l'insuffisance rénale
/
Indice APACHE
/
Insuffisance rénale chronique
/
Atteinte rénale aigüe
/
Maladies du rein
Type d'étude:
Etude diagnostique
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Humains
/
Mâle
langue:
Coréen
Texte intégral:
Korean Journal of Nephrology
Année:
2011
Type:
Article
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