Inflammatory reaction and alterations of pulmonary surfactant in Pseudomonas Aeruginosa pneumonia in immunocompromised rats / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 1099-1100, 2002.
Article
Dans Anglais
| WPRIM
| ID: wpr-340375
ABSTRACT
Pulmonary surfactant ( PS ) compromises lipids and surfactant proteins (SP) and lines on the alveolar air-liquid interface. It can reduce surface tension, prevent alveoli from collapse and reduce alveoli edema by disaturated dipalmitoylphosphatidylcholine. It also modulates the pulmonary immunology by SP-A and SP-D. In this study,we established a rat model of immunocompromised host (ICH) with pulmonary infection of Pseudomonas aeruginosa (P. aeruginosa), then studied its pulmonary inflammatory reaction and analyzed the concentration of lipids and SP-A in bronchoalveolar lavage fluid (BALF) during infection.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Physiologie
/
Protéolipides
/
Infections à Pseudomonas
/
Surfactants pulmonaires
/
Liquide de lavage bronchoalvéolaire
/
Chimie
/
Rat Sprague-Dawley
/
Pneumopathie bactérienne
/
Protéine A associée au surfactant pulmonaire
/
Protéines associées au surfactant pulmonaire
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Chinese Medical Journal
Année:
2002
Type:
Article
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