A new model for survival assessment based on the Chinese liver transplantation patients with hepatocellular carcinoma / 中华外科杂志
Chinese Journal of Surgery
; (12): 1023-1026, 2007.
Article
de Zh
| WPRIM
| ID: wpr-340868
Bibliothèque responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To establish a new model for liver transplantation recipients with hepatocellular carcinoma (HCC) and validate the feasibility of it.</p><p><b>METHODS</b>From February 1999 to June 2005, clinical data of 130 liver cancer patients who accepted liver transplantation were collected. Screening the pretransplant factors correlated with post-transplant survival using COX proportional-hazards regression, and establishing the assessment model. Finally, the area under the receiver operating characteristic curve (AUC ROC) were used to compare the validity of the new model with MELD.</p><p><b>RESULTS</b>Screened by the COX model, serum concentrations of alkaline phosphatase, alphafetoprotein, sodium and the number of tumor nodule were significantly related with post-transplant survival. The new model with these four variables had greater ability to assess post-transplant recipients' outcomes, however, the MELD had not evaluation capacity.</p><p><b>CONCLUSION</b>The established new model has a better ability to assess the risk of post-transplant mortality.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Sodium
/
Chirurgie générale
/
Sang
/
Alphafoetoprotéines
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Modèles des risques proportionnels
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Analyse de survie
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Chine
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Études de faisabilité
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Reproductibilité des résultats
/
Transplantation hépatique
Type d'étude:
Prognostic_studies
Limites du sujet:
Adult
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Aged
/
Female
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Humans
/
Male
Pays comme sujet:
Asia
langue:
Zh
Texte intégral:
Chinese Journal of Surgery
Année:
2007
Type:
Article