Analysis of survival rate and risk factors of liver retransplantation / 中华外科杂志

ABSTRACT

<p><b>OBJECTIVES</b>To analyze the survival rate of orthotopic liver retransplantation (Re-OLT) and identify the variables predicting the outcome.</p><p><b>METHODS</b>A retrospective analysis of 74 Re-OLT patients from January 1999 to December 2005 was performed. The univariate analysis of Kaplan-Meier model was used to investigate the relativity between the factors and survival rate, and COX regression model was used in multivariate analysis to identify the prognostic factors for survival.</p><p><b>RESULTS</b>The total incidence rate of Re-OLT was 5.7%, and overall patient survival rates at 1 month, 3 month, 1 year and 2 year were 82.4%, 73.8%, 71.9% and 68.5%, respectively. There were 10 factors might influence the survival rate by Kaplan-Meier model, such as the period of Re-OLT, stage of hepatic encephalopathy, prothrombin time, total bilirubin, warm ischemia time, operative surgical procedure, quantity of blood lost during operation, days staying in the intensive care unit (ICU), infection and complications after Re-OLT. And three factors among them were identified as independent prognostic factors for survival by multivariate model operative surgical procedure, days staying in the ICU and complications after Re-OLT.</p><p><b>CONCLUSION</b>The surgical procedure, duration in ICU and complications after Re-OLT are strong predictors for survival after Re-OLT.</p>