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Diagnosis and radiotherapy of germinomas arising in basal ganglia and thalamus / 中华外科杂志
Chinese Journal of Surgery ; (12): 979-981, 2007.
Article Dans Chinois | WPRIM | ID: wpr-340877
ABSTRACT
<p><b>OBJECTIVE</b>To summarize the clinical characteristic and radiotherapeutic effect of germinomas arising in basal ganglia and thalamus.</p><p><b>METHODS</b>The clinical data of 13 cases were reviewed retrospectively. All cases were pathologic diagnosis through stereotactic biopsy. Gamma-knife or ordinary irradiation were 2 cases respectively and the combined therapy with interstitial brachytherapy as foundation were 9 cases.</p><p><b>RESULT</b>All cases were male, median age of 16.1 years. Hemiparesis and ataxia were major symptoms, some cases were accompanied with precocious puberty. Imaging manifested intratumoral cystic components represented 76.9% of all lesions, calcification represented 30.8%, ipsilateral cerebral and brain stem hemiatrophy represented 46.2%, cerebral white matter invasion through internal capsule or corpus callosum represented 30.8%. One case died because of late complication and 12 cases had achieved satisfied therapeutic effect (the mean followed-up period was 40.6 months). Tumor-control were effective.</p><p><b>CONCLUSIONS</b>The clinical manifestation and imaging characteristics are helpful to diagnosis. Stereotactic biopsy make the affirmatory diagnosis. Operative total-removal is impossible because of deep location, neighbour of vital structure and invasion. The combined therapy with interstitial brachytherapy was effective.</p>
Sujets)
Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Radiothérapie / Chirurgie générale / Thalamus / Noyaux gris centraux / Tumeurs du cerveau / Études rétrospectives / Études de suivi / Résultat thérapeutique / Germinome / Diagnostic Type d'étude: Etude diagnostique / Étude observationnelle / Étude pronostique Limites du sujet: Adolescent / Adulte / Enfant / Humains / Mâle langue: Chinois Texte intégral: Chinese Journal of Surgery Année: 2007 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Radiothérapie / Chirurgie générale / Thalamus / Noyaux gris centraux / Tumeurs du cerveau / Études rétrospectives / Études de suivi / Résultat thérapeutique / Germinome / Diagnostic Type d'étude: Etude diagnostique / Étude observationnelle / Étude pronostique Limites du sujet: Adolescent / Adulte / Enfant / Humains / Mâle langue: Chinois Texte intégral: Chinese Journal of Surgery Année: 2007 Type: Article