Advances in the study of steroidogenic acute regulatory protein / 中华男科学杂志
National Journal of Andrology
;
(12): 733-736, 2006.
Article
Dans Chinois
| WPRIM
| ID: wpr-343531
ABSTRACT
The steroidogenic acute regulatory (StAR) protein is an essential component in the regulation of steroid biosynthesis in adrenal and gonadal cells. The StAR protein has a high tissue specificity, located on the mitochondrial membranes of some relative cells. It regulates the transfer of cholesterin from extracellular into intracellular and plays a dominant role in steroidogenic synthesis. Recent studies have also shown that the transcription and expression of StAR are modulated not only through the cAMP-PKA dependent pathway, but also by multiple hormones and cytokines, which contributes to the regulation of cholesterin synthesis.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Phosphoprotéines
/
Physiologie
/
Cholesterol side-chain cleavage enzyme
/
Régulation de l'expression des gènes
/
Cholestérol
/
Éthistérone
/
Génétique
/
Métabolisme
/
Mitochondries
Limites du sujet:
Animaux
/
Humains
langue:
Chinois
Texte intégral:
National Journal of Andrology
Année:
2006
Type:
Article
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