Observation of safety and efficacy of tadalafil for men with erectile dysfunction / 中华男科学杂志
National Journal of Andrology
;
(12): 421-427, 2006.
Article
Dans Chinois
| WPRIM
| ID: wpr-343607
ABSTRACT
<p><b>OBJECTIVE</b>To observe the safety and efficacy of tadalafil in the treatment of erectile dysfunction in clinical research.</p><p><b>METHODS</b>Eighty patients with ED, before and after 20 mg tadalafil administered orally, received respectively the rigiscan examination with aural and visual sexual stimulation at the same time, and then Bphallic circumference variation, stiffness index, duration were compared before and after the treatment.</p><p><b>RESULTS</b>Phallic stiffness index, duration revealed a statistically (P < 0.05) obvious improvement before and after the treatment for all patients. A significant difference (P < 0.01) on the phallic stiffness index, duration were found between the patients with psychogenic ED and others with organic or mixed ED after the treatment. Overall satisfaction with tadalafil was 82.5%. There was an obvious difference on the curative rates between the patients with psychogenic ED (92.3%) and others with organic ED (68.7%) or mixed ED (58.3%). All adverse events (11 cases of headache and dizziness, 8 cases of digestive canal unwell, 5 cases of flushing, 2 cases of back muscle pain) associated with tadalafil were mild and recovered without any treatment.</p><p><b>CONCLUSION</b>Tadalafil improves erectile function significantly in most patients. Adverse reactions are generally transient and mild to moderate in nature.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Inhibiteurs de la phosphodiestérase
/
Érection du pénis
/
Carbolines
/
Utilisations thérapeutiques
/
Traitement médicamenteux
/
Tadalafil
/
Dysfonctionnement érectile
Limites du sujet:
Adulte
/
Adulte très âgé
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
National Journal of Andrology
Année:
2006
Type:
Article
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