Steroids from Monascus purpureus metabolite / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the chemical constituents of Monascus purpureus metabolite.</p><p><b>METHOD</b>The compounds were isolated by column chromatography methods, and their structures were determined by spectroscopic methods.</p><p><b>RESULT</b>Eight compounds were isolated from the petroleum ether fraction of ethanolic extract and elucidated as stigmast-4-en-3-one (1), 3-oxo-24-methylenecycloarane (2), stigmasterol (3), 7beta-hydroxystigmasterol (4), 3beta-hydroxystigmast-5-en-7-one (5), 3beta-hydroxystigmast-5,22-dien-7-one (6), 5alpha, 8alpha-epidioxyergosta-6,22-dien-3beta-ol (7), sitosterol (8).</p><p><b>CONCLUSION</b>All of the compounds were isolated from this genu for the first time except compound 3 and 7.</p>