A Case of the Drug Reaction with Eosinophilia and Systemic Symptom (DRESS) Following Isoniazid Treatment / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
; : 27-30, 2015.
Article
de En
| WPRIM
| ID: wpr-34488
Bibliothèque responsable:
WPRO
ABSTRACT
The drug reaction with eosinophilia and systemic symptom (DRESS) syndrome is a severe adverse drug-induced reaction which includes a severe skin eruption, fever, hematologic abnormalities (eosinophilia or atypical lymphocytes) and internal organ involvement. The most frequently reported drug was anticonvulsants. The diagnosis of DRESS syndrome is challenging because the pattern of cutaneous eruption and the types of organs involved are various. The treatments for DRESS syndrome are culprit drug withdrawal and corticosteroids. Here we report a 71-year-old man with skin eruption with eosinophilia and hepatic and renal involvement that appeared 4 weeks after he had taken anti-tuberculosis drugs (isoniazid, ethambutol, rifampicin, and pyrazinamide), and resolved after stopping anti-tuberculosis drugs and the administration of systemic corticosteroids. DRESS recurred after re-challenging isoniazid, we identified isoniazid was causative drug.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Rifampicine
/
Peau
/
Tuberculose
/
Hormones corticosurrénaliennes
/
Diagnostic
/
Éosinophilie
/
Éthambutol
/
Fièvre
/
Syndrome d'hypersensibilité médicamenteuse
/
Isoniazide
Type d'étude:
Diagnostic_studies
Limites du sujet:
Aged
/
Humans
langue:
En
Texte intégral:
Tuberculosis and Respiratory Diseases
Année:
2015
Type:
Article