Early clinical presentations and MRI characteristics in newborns with cerebral infarction / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 96-99, 2009.
Article
de Zh
| WPRIM
| ID: wpr-347993
Bibliothèque responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>The present study aimed to characterize the clinical presentations and magnetic resonance imaging including conventional MRI and diffusion-weighted imaging (DWI) in newborns with cerebral infarction.</p><p><b>METHODS</b>Clinical records of 16 newborn infants with cerebral infarction were reviewed. All cases underwent DWI examination in addition to conventional MRI examination [T1-weighted (T1W) and T2-weighted (T2W)]within 5 days after birth. Five patients received the second MRI examination at the age of 11 to 18 days.</p><p><b>RESULTS</b>Eight patients had antenatal risk factors, 9 had intranatal risk factors, and no postnatal risk factors were found. Seizures as the first symptom were noted in 11 neonates, with a short duration and a low frequency. The first imaging examination (within 5 days) showed a slight hypointensity on T1W, a slight hyperintensity on T2W and significantly increased signal intensity with a clear boundary on DWI in the lesions. In the MRI re-examination, more obvious hypointensity on T1W and hyperintensity on T2W were noted, while hypointensity was shown on DWI in the lesions compared with the first imaging results.</p><p><b>CONCLUSIONS</b>Seizures characterized by short duration and low frequency usually may be the first symptom in newborns with cerebral infarction. A hyperintensity on DWI was shown in the lesions at the early stage of neonatal cerebral infarction. A hypointensity on T1W and a hyperintensity on T2W were demonstrated in the lesions with increasing disease duration.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Anatomopathologie
/
Encéphale
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Imagerie par résonance magnétique
/
Tomodensitométrie
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Infarctus cérébral
/
Diagnostic
Type d'étude:
Diagnostic_studies
Limites du sujet:
Female
/
Humans
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Male
/
Newborn
langue:
Zh
Texte intégral:
Chinese Journal of Contemporary Pediatrics
Année:
2009
Type:
Article