Influence of wen-yang herbs on hemodynamics in liver fibrotic rats / 中华肝脏病杂志
Chinese Journal of Hepatology
;
(12): 421-424, 2005.
Article
Dans Chinois
| WPRIM
| ID: wpr-348785
ABSTRACT
<p><b>OBJECTIVES</b>To observe the influence of wen-yang herbs on the hemodynamics in liver fibrotic rats.</p><p><b>METHODS</b>Wistar rats with liver fibrosis, induced by carbon tetrachloride and alcohol, were randomly divided into a treatment group and a control group. The treatment group was administered wen-yang herbs and the control group saline. At the end of the experiment, the hemodynamic markers of the liver and the mesentery, the liver function and hydroxyproline content of liver tissues between the two groups were compared. Blood volume of the livers and hydroxyproline content of liver tissues were also determined.</p><p><b>RESULTS</b>Blood volume of the liver and mesentery (P < 0.01) and blood flow velocity of small vein of mesentery (P < 0.05) of the treatment group were distinctly higher than the control group. The hydroxyproline content (P < 0.01) of the treatment group was remarkably reduced and liver function was improved.</p><p><b>CONCLUSION</b>Wen-yang herbs can activate microcirculation of the liver and mesentery, decrease the deposit of collagen in the liver and improve liver function.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Circulation sanguine
/
Médicaments issus de plantes chinoises
/
Répartition aléatoire
/
Rat Wistar
/
Utilisations thérapeutiques
/
Traitement médicamenteux
/
Cirrhose expérimentale
/
Phytothérapie
Limites du sujet:
Animaux
langue:
Chinois
Texte intégral:
Chinese Journal of Hepatology
Année:
2005
Type:
Article
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