Research advances on directional induction and differentiation in vitro from human pluripotent stem cells into erythrocytes / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 213-218, 2014.
Article
Dans Chinois
| WPRIM
| ID: wpr-349734
ABSTRACT
Red blood cell transfusion is an effective method to treat acute hemorrhage and severe anemia. However, blood source from donors is very limited, and transfusion-transmitted diseases occurred frequently, thus threatening human health. Therefore, the safe, abundant and functional blood source is needed. Generation of blood cells from human pluripotent stem cells(hPSC) will offer alternative approach. Lots of studies have been focused on erythroid cell differentiation in vitro, including how to enhance efficiency and improve their function. In this review, the research advances on differentiation methods and the regulatory mechanism are summarized. In addition, the progress in PSC differentiation into erythrocytes and the problems to be solved are discussed briefly.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Différenciation cellulaire
/
Biologie cellulaire
/
Érythrocytes
/
Cellules souches embryonnaires
/
Cellules souches pluripotentes induites
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Experimental Hematology
Année:
2014
Type:
Article
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