Effects of Siwu Tang on protein expression of HFCL / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1083-1086, 2006.
Article
de Zh
| WPRIM
| ID: wpr-351840
Bibliothèque responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effects of Siwu Tang on HFCL proliferation and protein expression of bone marrow stromal cells and to discuss molecular mechanism of enriching blood functions of Siwu Tang.</p><p><b>METHOD</b>MTT, flow cytometry and proteomics were used respectively to measure the effect of Siwu Tang on HFCL proliferation, cell cycle and proteinexpression.</p><p><b>RESULT</b>Siwu Tang can promote HFCL proliferation, increase proliferative index, up-regulate 12 kinds of proteins and down-regulate 5 kinds of proteins of HFCL.</p><p><b>CONCLUSION</b>Through promoting HFCL proliferation and acting on multipleprotein targets, the blood enriching function of Siwu Tang was exerted indirectly.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Pharmacologie
/
Plantes médicinales
/
Cellules de la moelle osseuse
/
Médicaments issus de plantes chinoises
/
Protéines
/
Cycle cellulaire
/
Lignée cellulaire
/
Chimie
/
Facteur de croissance fibroblastique de type 2
/
Cellules stromales
Type d'étude:
Diagnostic_studies
Limites du sujet:
Humans
langue:
Zh
Texte intégral:
China Journal of Chinese Materia Medica
Année:
2006
Type:
Article