Metabolism-related risk factors of cholelithiasis among Beijing residents: a case-control study / 中国医学科学院学报

ABSTRACT

<p><b>OBJECTIVE</b>To explore the metabolism-related risk factors of cholelithiasis among residents in Beijing.</p><p><b>METHODS</b>The clinical data including previous disease history, findings of physical examination, and results of cholecystosonography of 2270 patients with cholelithiasis identified in the Health Screening Center of Peking Union Medical College Hospital between August 2007 and August 2010 were retrospectively reviewed (the case group). Meanwhile, 4336 healthy individuals during the same period were randomly chosen as the control group.</p><p><b>RESULTS</b>Total cholesterol, triglyceride, low-density lipoprotein cholesterol, fasting blood glucose, body mass index, and systolic blood pressure were positively correlated with the incidence of cholelithiasis (P < 0.05), while high-density lipoprotein cholesterol was negatively correlated (P < 0.05). Diastolic blood pressure showed no association with cholelithiasis (P > 0.05).</p><p><b>CONCLUSION</b>Cholelithiasis is resulted from multiple factors including elevated blood lipids, blood glucose, and systolic blood pressure among residents in Beijing.</p>