Correlation between IL-6 levels and polymerized human serum albumin ceptor (PHSAR) in serum of chronic hepatitis patients / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 33-36, 2002.
Article
Dans Chinois
| WPRIM
| ID: wpr-355132
ABSTRACT
<p><b>BACKGROUND</b>To investigate the relationship between interleukin-6 (IL-6) levels in serum and HBV replication and the role of IL-6 in liver damage in chronic hepatitis B patients.</p><p><b>METHODS</b>Detected IL-6 levels and polymerized human serum albumin receptor (PHSA-R) in serum of different type of HBV markers positive patients and of different degree of chronic hepatitis B patients.</p><p><b>RESULTS</b>The results showed that the serum IL-6 levels were increased significantly in PHSA-R positive patients than in PHSA-R negative patients in chronic hepatitis B (P<0.01). The serum IL-6 levels were correlated with the levels of PHSA-R (r=0.694, P<0.01), and the degree of symptoms.</p><p><b>CONCLUSIONS</b>This study suggested that the IL-6 levels in serum of hepatitis B patients correlated HBV replication and the degree of liver damage, serum IL-6 levels may be used as a value indicating of HBV replication, the degree of symptoms and the effect of treatment.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Physiologie
/
Réplication virale
/
Sang
/
Virus de l'hépatite B
/
Interleukine-6
/
Récepteur albumine
/
Hépatite B chronique
Limites du sujet:
Adulte
/
Adulte très âgé
/
Humains
langue:
Chinois
Texte intégral:
Chinese Journal of Experimental and Clinical Virology
Année:
2002
Type:
Article
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