Sound level of conditioned stimulus differs the plasticity of characteristic frequency in the rat cortical neurons / 中国应用生理学杂志

ABSTRACT

<p><b>OBJECTIVE</b>Try to observe the plasticity of neuron in primary cortex of rat evoked by conditioned stimulus of different sound level.</p><p><b>METHODS</b>Applying conventional electrophysiological technique of extracellular recording to investigate the plasticity of characteristic frequency (CF) and frequency turning curve (FIC) of neurons in rat auditory cortex (AC) by determining CF shifts of neurons caused by sound stimulus of different sound level.</p><p><b>RESULTS</b>When the frequency difference between conditioned stimulus (CS) frequency and the CF of neuron was in 1.0 kHz, the plasticity of CF induced by CS was associated with sound level. The probability of the plasticity of CF evoked by CS of higher sound lever was more than the lower. And the probability was dependent on frequency turning curve (FTC) and almost independent on the sound level of conditioned signal.</p><p><b>CONCLUSION</b>Sound level of conditioned stimulus differs the plasticity of characteristic frequency of neurons in rat auditory cortex.</p>