A review of detection methods for human bocaviruses / 病毒学报
Chinese Journal of Virology
; (6): 298-302, 2014.
Article
de Zh
| WPRIM
| ID: wpr-356600
Bibliothèque responsable:
WPRO
ABSTRACT
Human bocavirus (HBoV) 1-4 have been detected both in respiratory and stool samples since the first HBoV was discovered in 2005. HBoV-1 is mostly associated with respiratory infection, while HBoV 2-4 are usually associated with intestinal tract infection. A variety of signs and symptoms have been described in patients with HBoV infection, including cough, wheezing, pneumonia, and diarrhea, but the research on pathogenic mechanism of HBoV is limited because HBoV cannot be cultured in vitro due to the lack of appropriate host cells. Three-dimensional epithelial cell culture, reverse genetics, and viral metagenomics are identified as novel tools that may promote the research on pathogenic mechanism of HBoV and the discovery of new viruses. This review summaries currently available diagnostic approaches such as electron microscopy, cell culture, PCR, and immunoassay in order to provide a method reference for indepth research on HBoV.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Protéines virales
/
Virologie
/
Virulence
/
Culture virale
/
Infections à Parvoviridae
/
Diagnostic
/
Bocavirus humain
/
Génétique
/
Métabolisme
/
Méthodes
Type d'étude:
Diagnostic_studies
Limites du sujet:
Animals
/
Humans
langue:
Zh
Texte intégral:
Chinese Journal of Virology
Année:
2014
Type:
Article