Quality standard for Xindi soft capsule / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 552-597, 2006.
Article
de Zh
| WPRIM
| ID: wpr-356772
Bibliothèque responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To establish the quality control standard of Xindi soft capsule.</p><p><b>METHOD</b>Quercetin, kaempferol and isorhamnetin were isolated by TLC with chloroform-ethyl formate-formic acid (5:4:1). The chromatographic separation was performed on a Diamonsil C18 column (4.6 mm x 250 mm, 5 microm). Acetonitrile-water-phosphoric (30:70:0.1) as mobile phase. The flow rate was 1 mL x min(-1) and column temperature was set at 40 degrees C. The UV detection wavelength was set at 254 nm.</p><p><b>RESULT</b>Quercetin, Kaempferol and Isorhamnetin could be identified by TLC. Quercetin showed a good linear relationship at a range of 0.412-1.648 microg, r = 0.999 9, the average recovery was 96.8%, and RSD was 0.9% (n = 6). Kaempferol showed a good linear relationship at a range of 0.021-0.083 microg, r = 0.999 8, the average recovery was 96.9%, and RSD was 2.0% (n = 6). Isorhamnetin showed a good linear relationship at a range of 0.183-0.732 microg, r = 0.999 9, the average recovery was 97.1%, and RSD was 1.6% (n = 6).</p><p><b>CONCLUSION</b>The method is accurate with the good reproducibility and can be used for the quality control of Xindi soft capsule.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Plantes médicinales
/
Contrôle de qualité
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Quercétine
/
Normes de référence
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Capsules
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Médicaments issus de plantes chinoises
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Chimie
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Reproductibilité des résultats
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Chromatographie sur couche mince
/
Hippophae
Type d'étude:
Prognostic_studies
langue:
Zh
Texte intégral:
China Journal of Chinese Materia Medica
Année:
2006
Type:
Article