Donations after cardiac death kidney transplantation in northwest China / 南方医科大学学报
Journal of Southern Medical University
; (12): 414-418, 2014.
Article
de Zh
| WPRIM
| ID: wpr-356909
Bibliothèque responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore the effect of donations after cardiac death (DCD) kidney transplant performed in northwest China and the measures for management of delayed graft function (DGF).</p><p><b>METHODS</b>In the period of 2011-2013, a total of 51 families of DCD donor gave their consent to organ donation by signing the informed consent with the help by a Red Cross Organization (ROC) coordinator, and 102 kidneys were retrieved by organ procurement organization (OPO) teams. Ninety-four operations of renal transplantation were carried out in our hospital. All the patients were followed-up and based on the occurrence of DGF after transplantation, they were divided into DGF group and non-DGF group for comparative studies.</p><p><b>RESULTS</b>The success rate of donation after cardiac death was 29.3%, and the incidence of post-transplantation DGF was 27.7%. The 1-year human/kidney survival rate was 98.9%/95.7%. Within six months after the transplant, the values of eGFR in DGF group were significantly lower and serum creatinine significantly higher than those in non-DGF group (P<0.05), but no significant differences were found between the two groups thereafter (P>0.05). The occurrence of DGF in LifePort mechanical perfusion cohorts was significantly lower than that in the simple cold preservation group (21.5% vs. 41.4%, P<0.05).</p><p><b>CONCLUSION</b>The overall effect of DCD kidney transplant is good despite a high incidence of early DGF, and we recommend the use of low-temperature mechanical perfusion for storage and transportation of DCD donor kidney.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Acquisition d'organes et de tissus
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Chine
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Transplantation rénale
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Mort
/
Reprise retardée de fonction du greffon
Limites du sujet:
Adult
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Female
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Humans
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Male
Pays comme sujet:
Asia
langue:
Zh
Texte intégral:
Journal of Southern Medical University
Année:
2014
Type:
Article