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Laboratory research of the influence of keyouling on the proliferation of human prepuce epidermis cells and condyloma acuminatum cells / 中华男科学杂志
Zhonghua nankexue ; Zhonghua nankexue;(12): 237-239, 2004.
Article de Zh | WPRIM | ID: wpr-357039
Bibliothèque responsable: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To discuss the mechanism of the Chinese medicine Keyouling in the treatment of condyloma axuminatum (CA).</p><p><b>METHODS</b>Human prepuce epidermis cells and CA cells were primarily cultured and subcultured. We determined the proliferation of human prepuce epidermis cells and CA cells, and observed the influence of Keyouling with different concentrations on the proliferation of human prepuce epidermis cells and CA cells by means of MTT colourimetry assay.</p><p><b>RESULTS</b>The absorbance was directly proportional to the numbers of human prepuce epidermis cells (r = 0.9850, P < 0.001) and CA cells (r = 0.9892, P < 0.001). Keyouling had no effect on proliferation of the human prepuce epidermis cells, but it had significant inhibition on CA cells. The concentrations of Keyouling bore negative correlation with the proliferation percentage of CA cells(r = -0.4124, P < 0.01).</p><p><b>CONCLUSION</b>Keyouling can significantly restrain the growth and proliferation of CA cells but has no damaging effect on normal organic cuticle cells. It is suggested that Keyouling might have anti-HPV effect.</p>
Sujet(s)
Texte intégral: 1 Indice: WPRIM Sujet Principal: Anatomopathologie / Maladies du pénis / Pénis / Pharmacologie / Peau / Médicaments issus de plantes chinoises / Condylomes acuminés / Division cellulaire / Utilisations thérapeutiques / Relation dose-effet des médicaments Limites du sujet: Adolescent / Adult / Humans / Male langue: Zh Texte intégral: Zhonghua nankexue Année: 2004 Type: Article
Texte intégral: 1 Indice: WPRIM Sujet Principal: Anatomopathologie / Maladies du pénis / Pénis / Pharmacologie / Peau / Médicaments issus de plantes chinoises / Condylomes acuminés / Division cellulaire / Utilisations thérapeutiques / Relation dose-effet des médicaments Limites du sujet: Adolescent / Adult / Humans / Male langue: Zh Texte intégral: Zhonghua nankexue Année: 2004 Type: Article