Expression of CD44v6 and E-cadherin in prostate carcinoma and metastasis of prostate carcinoma / 中华男科学杂志
National Journal of Andrology
;
(12): 32-38, 2004.
Article
Dans Chinois
| WPRIM
| ID: wpr-357089
ABSTRACT
<p><b>OBJECTIVE</b>To study the expression of CD44v6 and E-cadherin(ED) in prostate carcinoma in relation to the metastasis of prostate carcinoma.</p><p><b>METHODS</b>The expression of CD44v6 and ED in 45 cases of prostate carcinoma was studied with immunohistochemical technique.</p><p><b>RESULTS</b>The positive expression rates of CD44v6 and ED in prostate carcinoma were 77.8% and 48.9%, respectively. The high level expression of CD44v6 and the low level expression of ED were positively correlated with differentiation, clinical staging and metastasis of prostate carcinoma (P < 0.05). The expression of CD44v6 was negatively correlated with ED(r = -0.58, P < 0.005).</p><p><b>CONCLUSIONS</b>The expression of CD44v6 and ED protein might be a useful marker for prostate carcinoma in evaluating the biological behavior and prognosis of the tumor.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Tumeurs de la prostate
/
Immunohistochimie
/
Glycoprotéines
/
Cadhérines
/
Différenciation cellulaire
/
Chimie
/
Antigènes CD44
/
Métastase tumorale
Limites du sujet:
Humains
/
Mâle
langue:
Chinois
Texte intégral:
National Journal of Andrology
Année:
2004
Type:
Article
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