A study of aspermia-related genes by genchips and analysis of the RAP1A gene / 中华男科学杂志
National Journal of Andrology
;
(12): 654-657, 2003.
Article
Dans Chinois
| WPRIM
| ID: wpr-357117
ABSTRACT
<p><b>OBJECTIVE</b>To study the differential gene expression profiles between the normal and aspermia human testes by genechips.</p><p><b>METHODS</b>Probes were prepared from mRNA extracted from both normal and aspermia testes and employed on Biostar H-40s genechips to detect the differential gene expression profiles. A distinctly up-regulated gene RAP1A was analyzed by bibliogrphic retrieval.</p><p><b>RESULTS</b>Six hundred and twenty-three differential expressed genes were found, among which the distinctly up-regulated gene RAP1A was closely related to human sperm regulation.</p><p><b>CONCLUSIONS</b>Screening the differential gene expression profiles between the normal and aspermia human testes by genechips can be used in the study of aspermia-related genes.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Oligospermie
/
Séquençage par oligonucléotides en batterie
/
Protéines G rap1
/
Analyse de profil d'expression de gènes
/
Génétique
/
Méthodes
Limites du sujet:
Adulte
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
National Journal of Andrology
Année:
2003
Type:
Article
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