Research on hemostatic effect of total saponins of yinfenglun / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To research the hemostatic effect of total saponins of Yinfenglun.</p><p><b>METHOD</b>Bleeding time and volume were deteminded in mice after tails being cut. Clotting times were researched on mice, rats and dogs. Hemostatic mechanism total saponins of Yinfenglun were studied on plasma recalcified time, PT, KPTT and ELT.</p><p><b>RESULT</b>TSY at different doses could markedly shorten bleeding time, reduce bleeding volume in mice. TSY also could shorten clotting time of mouse, rat and dog. TSY could influence both intrinsic coagulatian system and extrinsic coagulatian system,and had no effect of antifibrinolysis.</p><p><b>CONCLUSION</b>There were obvious hemostatic effect of total saponins of Yinfenglun.</p>