Improved methods for researching isolated carotid sinus baroreceptors automatically controlling for sinus pressure / 中国应用生理学杂志
Chinese Journal of Applied Physiology
;
(6): 11-14, 2013.
Article
Dans Chinois
| WPRIM
| ID: wpr-358692
ABSTRACT
<p><b>OBJECTIVE</b>To develop a system for automatically controlling carotid sinus pressure in the study on baroreceptors.</p><p><b>METHODS</b>The preparation containing carotid sinus with parts of the connected vessels and carotid sinus nerve (CS-CSN) were isolated and perfused. A critical pressure controlling component (PRE-U, Hoerbiger, Deutschland) dictated by a computer was integrated into the system to clamp the intrasinus pressure. The pressure command and the relevant intrasinus pressure were compared to evaluate the validity of the pressure controlling system.</p><p><b>RESULTS</b>A variety of sinus pressure-controlling patterns, including pulsation, ramp and step pressures, could be achieved accurately by using the system, and the pressure-dependent discharge activities of sinus nerve were confirmed.</p><p><b>CONCLUSION</b>This system for clamping carotid sinus pressure could realize multiple pressure-controlling patterns and is a useful and flexible pressure controlling method that could applied in the study on mechano-electric transduction of baroreceptors.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Physiologie
/
Barorécepteurs
/
Pression sanguine
/
Sinus carotidien
/
Neurofibres
Limites du sujet:
Animaux
langue:
Chinois
Texte intégral:
Chinese Journal of Applied Physiology
Année:
2013
Type:
Article
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