Ultrastructural changes of hepatocyte fibrogenesis in cholelithiasis / 中华肝脏病杂志
Chinese Journal of Hepatology
;
(12): 924-926, 2010.
Article
Dans Chinois
| WPRIM
| ID: wpr-360796
ABSTRACT
<p><b>OBJECTIVE</b>To explore the ultrastructural changes of hepatocyte fibrogenesis in cholelithiasis in biliary tract.</p><p><b>METHODS</b>l0 liver biopsies were taken from the patients suffered from gallstone and choledocholithiasis during surgical treatment and the ultrastructural changes were observed under electromicroscope.</p><p><b>RESULTS</b>There were plentiful collagenous microfibrils (CMFs) grown within some hepatocytes. These CMFs distributed locally or diffusely in cytoplasm even extended into nucleus. In 7 cases numerous megamitochondrias appeared in several hepatocytes, the inclusions mimicking fibrils could be frequently seen and grew beyond the envelope. Furthermore, typical CMFs could be seen in the large microbodies, and several vesicular or cystic structures similar as fibroblast were presented in marginal areas of the hepatocytes.</p><p><b>CONCLUSIONS</b>We deduce that the fibrosed hepatocytes may be remained and take part in the hyperplasia of hepatic fibrous tissue.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Lithiase biliaire
/
Hépatocytes
/
Cirrhose du foie
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Chinese Journal of Hepatology
Année:
2010
Type:
Article
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