Clinical significance of expression of VEGF and bFGF in thyroid carcinoma / 中华外科杂志
Chinese Journal of Surgery
;
(12): 864-866, 2004.
Article
Dans Chinois
| WPRIM
| ID: wpr-360944
ABSTRACT
<p><b>OBJECTIVE</b>To study the clinical significance of expression of VEGF and bFGF in thyroid carcinoma.</p><p><b>METHODS</b>Immunohistochemical SP technic was used to investigate the expression of VEGF and bFGF in 90 cases of papillary carcinoma, 14 cases of undifferentiated carcinoma, 10 cases of normal thyroid tissue.</p><p><b>RESULTS</b>The positive rate of VEGF and bFGF in thyroid carcinoma was 63.5% and 59.6% respectively, Which was significantly higher than that in normal thyroid tissue (P < 0.01); The positive rate of VEGF and bFGF in undifferentiated carcinoma was 92.9% and 85.7% respectively, which was significantly higher than that in papillary carcinoma (P < 0.05); The positive rate of expression of VEGF and bFGF was correlated with lymph gland metastasis (P < 0.05); A positive correlation between these two expresses existed in thyroid carcinoma (gamma = 0.596, P < 0.05).</p><p><b>CONCLUSION</b>VEGF and bFGF can be regarded as a parameter to evaluate the biological behavior and prognosis of thyroid carcinoma.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Tumeurs de la thyroïde
/
Immunohistochimie
/
Carcinomes
/
Carcinome papillaire
/
Facteur de croissance fibroblastique de type 2
/
Facteurs de croissance endothéliale vasculaire
/
Métastase lymphatique
/
Métabolisme
Type d'étude:
Étude pronostique
Limites du sujet:
Adolescent
/
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Chinese Journal of Surgery
Année:
2004
Type:
Article
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