Inhibitory Effect of Ougi-keisi-gomotu-to on oxidative stress / 日本東洋医学雑誌
Kampo Medicine
;
: 177-183, 1997.
Article
Dans Japonais
| WPRIM
| ID: wpr-368220
ABSTRACT
It has been suggested that various neurological diseases (particularly those accompanying aging, the cranial nerves, etc.) involve oxidative stress. Some of these diseases have been successfully controlled with traditional herbal medicine. In the present study, Ougi-keishi-gomotsu-to, reported to be effective against subacute myelo-opticoneuropathy (SMON), showed an inhibitory effect on lipid peroxidation of homogenate by hydroxy radical, a type of active oxygen derived from the interaction of Fe<sup>3+</sup> and 8-hydroxyquinoline. 8-hydroxyquinoline is a homologue of chinoform, which is causally related to the pathogenic process of SMON. It has also been indicated that Ougi-keishi-gomotsu-to has a hydroxy radical scavenger with radical-quenching effects. It is, therefore concluded that Ougi-keishi-gomotsu-to has an inhibitory effect on oxidative stress.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Japonais
Texte intégral:
Kampo Medicine
Année:
1997
Type:
Article
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