The Effects of Pre-Acupuncture on Rat's Stomach Ulcer Induced by Water Immersing Stress (II) / 全日本鍼灸学会雑誌

ABSTRACT

In a previous paper, we reported that acupuncture on the equivalent loci to human CV-12, BI-12 and ST-36 inhibited rat's stomach ulcer induced by water immersing stress. In this paper, we report the influence of acupuncture on the equivalent loci to human BL-21 and ST-36.<br>Method<br>15 male Wister rats of about 200g in weight were divided into the test group (6 rats) and the control group (9 rats), and acupuncture was administered to the test group on the equivalent loci to human BL-21 and ST-36 every other day. The next day after the sixth acupuncture, they were immersed in the water of 23°C to their chests 7 hours and the stomachs were extirpated from them and the gastic glands were sliced and stained in hematoxylin-erosion. Making a microscopic examination of these slices, we evaluated the number of mucoclasis classified by strength, depth and width.<br>Effect<br>More than 90% of mucoclasis showed erosion of tissue. It was less than 2/4 in depth and less than 500μ in width.<br>1. Erosion in each slice numbered 20.3±5.6:34.1±9.5 in average between the two groups and it showed significantly small number in the test group (p<0.01).<br>2. The number of erosion in depth was much smaller in the test group (p<0.01, p<0.05).<br>less than 1/4…19±4.2:28.1±6.1<br>less than 2/4…1.3±1.5:5.3±4.0<br>3. The number of erosion in width was also much smaller in the test group (p<0.05)<br>10μ-500μ…10.3±4.7:19.8±9.4<br>Conclusion<br>It was showed that pre-acupuncture inhibited stress erosion.