Molecular Testing of Lymphoproliferative Disorders: Current Status and Perspectives
Journal of Pathology and Translational Medicine
;
: 224-241, 2017.
Article
Dans Anglais
| WPRIM
| ID: wpr-38102
ABSTRACT
Molecular pathologic testing plays an important role for the diagnosis, prognostication and decision of treatment strategy in lymphoproliferative disease. Here, we briefly review the molecular tests currently used for lymphoproliferative disease and those which will be implicated in clinical practice in the near future. Specifically, this guideline addresses the clonality test for B- and T-cell proliferative lesions, molecular cytogenetic tests for malignant lymphoma, determination of cell-of-origin in diffuse large B-cell lymphoma, and molecular genetic alterations incorporated in the 2016 revision of the World Health Organization classification of lymphoid neoplasms. Finally, a new perspective on the next-generation sequencing for diagnostic, prognostic, and therapeutic purpose in malignant lymphoma will be summarized.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Organisation mondiale de la santé
/
Lymphocytes T
/
Lymphome B
/
Classification
/
Hybridation fluorescente in situ
/
Cytogénétique
/
Diagnostic
/
Anatomopathologie moléculaire
/
Lymphomes
/
Syndromes lymphoprolifératifs
Type d'étude:
Etude diagnostique
/
Guide de pratique
/
Étude pronostique
langue:
Anglais
Texte intégral:
Journal of Pathology and Translational Medicine
Année:
2017
Type:
Article
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