Research development on drug resistance of taxol and β tubulin Ⅲ / 肿瘤研究与临床
Cancer Research and Clinic
; (6): 137-139, 2011.
Article
de Zh
| WPRIM
| ID: wpr-382695
Bibliothèque responsable:
WPRO
ABSTRACT
The taxol s effect of inducing apoptosis is mainly related to its ability to promote tubulin polymerization and prevent tubulin chain depolarization. Drug resistance is the main restriction factor for clinical usage of taxol. Some basic and clinical studies support that poor response to taxol and poor prognosis are related to overexpression of β tubulin Ⅲ.
Texte intégral:
1
Indice:
WPRIM
Type d'étude:
Prognostic_studies
langue:
Zh
Texte intégral:
Cancer Research and Clinic
Année:
2011
Type:
Article