Study on IgA Fc receptor-mediated neutrophil degranulation / 中华微生物学和免疫学杂志
Chinese Journal of Microbiology and Immunology
;
(12): 121-125, 2001.
Article
Dans Chinois
| WPRIM
| ID: wpr-384074
ABSTRACT
Objective To investigate the pattern of human neutrophil degranulation mediated by Fc alpha receptors. Methods IgA immune complexes (IgA IC) and specific monoclonal antibody were used to stimulate neutrophil degranulation. Lactoferrin released by stimulated neutrophils was quantitatively determined. Results Monoclonal antibody and IgA IC could both induce neutrophil lactoferrin release. However, monoclonal antibody induced rapid and strong degranulation whilst the effect of IgA IC was much weaker. Conclusion The pattern of neutrophil degranulation induced by IgA IC and monoclonal antibody is different.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Journal of Microbiology and Immunology
Année:
2001
Type:
Article
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